A review of the works of Martyr Sadr shows that the Holy Quran, from the point of view of this thinker, is an epistemological source for discovering and explaining the realities of human life. This approach, in fact, has set its goal to derive the theories of human sciences from the knowledge source of the Qur'an; Because science results from the accumulation of theories, and discovering and explaining the realities of human life is the same goal of human sciences. Of course, merely claiming Quranic theorizing is one thing, and methodically discovering it is another. The author of the article believes that "thematic interpretation of Sadr" is actually the method of extracting theories of Quranic humanities, at the level of basic theories of humanities. However, other theories in other layers, from the point of view of this character, have other methods. Therefore, this article aims to fill the methodological gap in Quranic humanities studies to provide a methodological explanation of the thematic interpretation of Sadr. In this regard, it is clear that Sadr's thematic interpretation has a methodological identity and this style of interpretation, in his ijtihad-scientific system, is the same method of exploring Quranic theories in the human field. In this approach, the scientific authority of the Qur'an is also established in the human sciences.

In this research, ijtihad methodology is used. Also, according to the nature of the humanities of the topics, comparative strategies are used in the meta-paradigmatic scale and meta-analysis in related topics.